Brief Info About Medicine
All Information published below is from public sources and cannot be used as expert's opinion. We request you to consult your doctor for more information
1Why Is it Used ?
LOPERAMIDE :
Adult: PO Acute diarrhoea As HCl: Inital: 4mg, then 2 mg after each loose stool. Usual dose: 6-8 mg/day. As oxide: Inital: 2-4 mg, then 1 mg after each loose stool. Max: 16 mg/day (as HCl) or 8 mg/day (as oxide). Chronic diarrhoea As HCl: Initial: 4-8 mg/day in divided doses. Max: 16 mg/day.
2What are the Side Effects ?
LOPERAMIDE :
Abdominal pain, distention, and discomfort; paralytic ileus; constipation, dry mouth, drowsiness, dizziness, fatigue, rash.
Potentially Fatal: Toxic megacolon.
3What Precautions should be taken ?
LOPERAMIDE :
Concomitant specific therapy must be given in those with infectious diarrhoea; hepatic dysfunction; infants; pregnancy, lactation
4Do not take this if you have any of the below ...
LOPERAMIDE :
Conditions when inhibition of peristalsis is undesirable (e.g. ileus or megacolon); antibiotic induced colitis; active inflammatory bowel disease; if abdominal distention develops during use; abdominal pain in the absence of diarrhoea.
5Interaction with other medicines...
LOPERAMIDE :
Bioavailability increased by co-trimoxazole, ritonavir, saquinavir. Respiratory depression reported when administered with quinidine. Loperamide increases GI absorption of desmopressin and decreases exposure to saquinavir.
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